I read books, I write about books, I would probably marry a book if I could find one who liked me enough. Three words to describe me mature, irresponsible, contradictory, unreliable...oh...that's four...
It's difficult to know what to say about this book without picking it apart, which would be a serious disservice to this story in particular. Reading Annihilation is submerging yourself into a sense of creeping dread. It's not the sort of horror that jumps out and says Boo. Instead it is the sort that makes you feel unsettled, like awaking from a disturbing dream. This is both the real strength of the book, and also the reason I can't say I completely enjoyed it. (Due to a history of anxiety I'm not especially fond of media that stirs up uneasiness.) Add in a dash of isolation, as the whole story takes place far removed from civilization, and the resulting mood ends up feeling similar to a mesh between Lovecraft and LOST.
This book is more of a character study, and a setting exploration, than a plot piece. You dive not only into the mysterious Area X, but also the mind of the POV character, the biologist. I really appreciated how lush the descriptions were with biological details - it not only fleshed out the setting, but it illustrated the way she sees the world. When you get deeper into the story it's hard to imagine a different perspective being anywhere near as effective. I should also mention that even though I was never quite certain how I personally felt about the biologist I did think she was a well formed, round, and convincing female character. And the prose was well formed and engaging.
When it comes down to it most of the things I have to say about this book are positive. It's a really strong addition to New Weird fiction. If delving into a story that taps into the uncertain and the bizarre, and can have multiple interpretations, then this might be your cup of tea.